The goals of treatment for leptomeningeal disease (LMD) are to prolong survival & improve or stabilize neurological symptoms
Selecting which options are best for your particular case will depend upon the recommendations from the doctor guiding your treatment, as well as your own personal preferences.
Depending on your breast cancer subtype, chemotherapy, endocrine therapy, immunotherapy, and/or targeted therapy may be used to treat LMD. Radiation therapy may also be recommended, particularly to relieve pain or neurological symptoms. All interventions mentioned below can be used in combination, sometimes simultaneously. For example, a patient with LMD may receive IV chemotherapy to control the cancer outside of the central nervous system; intrathecal chemotherapy to control the LMD; and radiation therapy to address issues with pain.